Severely immunocompromised or immunosuppressed individuals do not have the ability to mount an appropriate response to any microbe that they come in contact with. Specialised cells in the intestine (M Cells & Peyers patches) are continually sampling the intestinal lumen for antigens (food or microbes). Microbes, even those that are normally neutral or considered beneficial, can sometimes cross the gut barrier and grow in the blood or in the internal organs where the nutrients are high and the competition for nutrients is low. Growth in these areas can cause septicaemia, fungemia, abscesses, myo-endocarditis (infection of the heart), or pancreatitis.

There may in fact be a benefit in taking probiotics for patients with severe immunosuppression, but the risk is also thought to be high in many circumstances. Due to currently insufficient clinical evidence around this area, at OptiBac Probiotics we do not recommend probiotics for individuals who are severely immunocompromised or immunosuppressed.


New study says certain probiotics don't prevent diarrhoea & C. difficile

Posted 2nd Sep 2014

A new study carried out here in the UK has found that some strains of probiotics are ineffective at preventing antibiotic-associated diarrhoea (AAD) and C. difficile diarrh...

Is your gut bacteria influencing your food cravings?

Posted 29th Aug 2014

Do you blame your own will power when it comes to holding off junk food? Perhaps you can blame it on your gut bacteria!  Many of us think that we only have one...

Gut bacteria, allergies and probiotics on BBC's Horizon

Posted 28th Aug 2014

Did anyone see Horizon last night on BBC2? The programme entitled ‘Allergies: Modern Life and Me’ looked at the possible causes behind the modern epidemic in childho...

New meta analysis of probiotics for constipation

Posted 27th Aug 2014

A new meta-analysis of probiotics for constipation has been published in the American Journal of Clinical Nutrition. Constipation is a common condition which the NHS estima...