Of course every live cultures brand will claim to be the best, and at the end of the day what's best for you may not be the best for your friend. But thank you in advance for taking a moment to read this page, and we hope you'll agree that we at OptiBac truly offer some of the very best live cultures in the UK, if not worldwide!

Read why OptiBac Probiotics are the bestWhen it comes to finding the ‘best’ live cultures there are a number of questions to ask. Do you want the best in terms of research, customer reviews, or value? Perhaps you know that different friendly bacteria will work in different ways, and you simply want the best supplement for you. Let's look at 5 important factors to finding the best live cultures.

1) Reviewed and Recommended

We are so happy to receive plenty of feedback from consumers, and it is not unusual to read reviews such as ‘life changing’, and ‘I don’t know what I did without them!’ Our reviews are all collected by a third party to ensure reviewers are independently verified as real customers. Take a look at some of the feedback; we reckon we boast the best and the most plentiful reviews on probiotics you will find.

Probiotics reviews May 2015
A few recent reviews of our supplements - read more of our customer reviews here

As well as a constant stream of positive feedback from consumers, the OptiBac range is recommended by celebrity nutritionists including Ian Marber, Vicki Edgson, Kirsty Henshaw, Glen Matten, healthy chef Natasha Corrett, fitness fanatics Carly Rowena and the Lean Machines, Alexander Ferentinos, and raw food chef Tanya Maher. This is alongside thousands more practitioners and doctors across the UK, Ireland and around the world.

If you are recommending OptiBac in your shop, you are in good company. It is the most recommended live cultures range by nutritionists in Whole Foods Market, Planet Organic, and thousands of independent health food shops, pharmacies and clinics around the UK & Ireland. OptiBac can also be found in numerous wellbeing spaces such as the Grayshott Spa, Wakeman Road and London's coolest class only gym, Frame.

We’ve also been thrilled to be featured in various publications including Red magazine, the Daily Mail, Woman & Home, Hello, Cosmopolitan and Woman magazine. More press mentions can be found on the blog.

2) Most Researched Live Cultures

The OptiBac range offers you some of the most researched strains (types) in the world.

If you're looking for the best live cultures supplement out there, it may well make sense to look for the most researched. There are different levels of research; the two key types are 'in-vitro' and 'in-vivo'. In-vitro research means ‘test tube’ experiments in the lab, where strains of live cultures are tested for different criteria, eg. the ability to survive at room temperature. You may have heard that it is important to choose a live culture that survives to reach the gut alive. This is true. All of our supplements are tested and guaranteed1 to do so, and without the need for extra gimmicks such as enteric coating. Healthcare practitioners can read more about our in-vitro tests, in this analysis by nutritional therapist Joanna.

probiotic brands research compared
Comparing research across live cultures brands

As well as in-vitro tests, a high quality probiotic will be backed up with in-vivo research (ie. tests on living beings as opposed to in a test tube), and even better, with clinical trials. This is something that many friendly bacteria supplements, foods and drinks on the market do not have. We counted the number of clinical trials on products in our range, and looked at these in comparison to other brands on the UK market. The graph above depicts true counts, and includes all other major brands in your store.

Healthcare professionals can read more about our brand research comparison, or see a good overview of our clinical trials.2

3) Specific Strains

At the end of the day the 'best live cultures' for you will most likely not be the best for your friend. Research into live cultures continues to grow, and continues to demonstrate that different types, or strains of live cultures will have different modes of action in the body3. So it is essential to find the right type of friendly bacteria for you!

At OptiBac, we look at specific strains. Not only do we offer you some of the world’s most researched strains of live cultures, but we look at the aims and findings of the trials in question, and target the product accordingly.

Browse our online shop to look at the 12 different products, or get in touch if you are unsure which one is right for you.

4) Excellent Value for Money

Whilst the OptiBac supplements are not always the cheapest on the market, certainly when you look at strength and quality, they are some of the best value products. We are not big on flashy, expensive packaging and we keep margins low in order to offer you and your customers the best value for money. For example, if you are looking to buy the strain Saccharomyces boulardii in its pure form, you will find no cheaper alternative on the UK market when you look into the number of capsules per pack, as well as the strength per capsule. Prices start at £3.25, as you will see on the shop.

5) Caring Company

It might also interest you to hear that we really care! We support numerous charities with our work, including the fantastic international women’s rights organisation, Womankind Worldwide, with every purchase of our OptiBac For women; and the Aga Khan University Hospital’s Patient Welfare Programme in East Africa. We’re a UK, family run business (my brother, sister and I - pictured below - run the business together, and are lucky to be backed by an incredibly knowledgeable team, with over 10 qualified in nutrition), and we’re all completely passionate about natural health. So if all of that doesn’t make us the best company to look to for your live cultures, we don’t know what does!

Find out more about the people behind our company here, or our charitable donations and wider values here.

Thanks so much for giving us a chance to explain why we think we deserve the ‘best’ status! What do you think? Let us know your thoughts below.

Best of the Best?

So now you know our range of live cultures is the best... Which is the best product from our range? Well as we explained in reason number 3, it all depends on your individual needs. Browse the products on the shop, take a look at our FAQs and think about the best option for you. Sometimes it even requires a bit of trial and error, but stick with it and you'll find one that works for you. If you really need a quick answer, and you just want a general live cultures supplement, check out 'For every day EXTRA Strength'. You may have heard of acidophilus - well, this contains the most researched strain of acidophilus in the world. Not bad, right?

Notes & References

1. In-vitro tests; including those for shelf-stability, adhesion capabilities,survival of gastric acidity & bile salts,and inhibition of pathogens; are published in internal reports and available at request from trade and healthcare professionals. Additionally a number of the test results can be seen on this page: www.optibacprobiotics.co.uk/blog/2014/09/our-response-to-recent-study-probiotic-claims

2. Full list of references for all published clinical trials available on request, and for professional use only.

3. Many examples could be referenced here, but if we look at a specific area such as children's health, one can see three different outcomes in trials using different strains: 1) Maydannik, V. et al (2010) Efficiency and safety of Lacidofil in children with antibiotic-associated diarrhoea caused by Clostridium difficile. Paediatrics, Obstetrics and Gynaecology 3 53-57. 2) Mohan, R. et al (2006) Effects of Bifidobacterium lactis BB12 supplementation on intestinal microbiota of preterm infants: a double-blind, placebo-controlled, randomised study. J Clin Microbiol 44 11 4025-31 and 3) Cazzola, M. (2010) Efficacy of a synbiotic supplementation in the prevention of common winter diseases in children: a randomised, double-blind, placebo-controlled pilot study. Ther Adv Respir Dis 4 5 271-8

4. Matsumoto, M. et al. (2001) Effect of Yoghurt with Bifidobacterium lactis Bb-12® in Improving Fecal Microflora and Defecation of Healthy Volunteers. Journal of Intestinal Microbiology; 14(2): pp. 97-102

5. Pitkala, K.H et al. (2007) Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial. Journal of Nutritional Health and Aging; 11(4): pp.305-311.

6. Nishida, S. et al. (2004) Effect of Yoghurt Containing Bifidobacterium lactis BB-12® on Improvement of Defecation and Fecal Microflora of Healthy Female Adults. Milk Science; 53(2): pp. 71-80 and more at http://www.optibacprobiotics.co.uk/scientific-research/bifidobacteria-fibre-research

7. McFarland, L.V. & Bernasconi, P. (1993) Saccharomyces boulardii: A Review of an Innovative Biotherapeutic Agent. Microbial Ecology in Health and Disease; Vol. 6 pp. 157-171.

8. Hochter, W. et al (1990) Saccharomyces boulardii in acute adult diarrhea. Efficacy and tolerance of treatment. Munchener Medizinische Wochenschrift; Vol. 132 (12) pp. 188-192.

9. Ducluzeau, R. & Bensaada, M. (1982) Comparative effect of a single or continuous administration of Saccharomyces boulardii on the establishment of various strains of Candida in the digestive tract of gnotobiotic mice. Annales de microbiologie. (Inst. Pasteur). 133: pp: 491-501 and for more research on S. boulardii visit https://www.optibacprobiotics.co.uk/scientific-research/saccharomyces-boulardii-research


  • I've been an Optibac customer for many years, and am very happy with the products, service, and family feel to the company. These probiotics have served me and my friends' tummies very well - and I remember trying other brands in the past, and being disappointed (and surprised) that they had nowhere near the same effect! Now I am sure to keep plenty of Optibac at home. Didn't know you were involved with Womankind - I know of this charity as one doing great things. So keep up the good work guys, it all sounds brill.

  • Optibac range has always worked with and my friends. I wouldn't change it for a different one at all!

  • Does your in vivo testing involve animals or are they conducted on humans?

  • I had a two hour phone call with one of your professionals and was most impressed with the knowledge and willingness to spend time answering my questions. I always recommend Optibac to my clients as I have absolute faith you really care about your customers health.

  • Hi Theresa,

    Thanks for your question.
    Scientific research necessitates the use of both ‘in vitro’ and ‘in vivo’ studies: ‘in vitro’ referring to laboratory testing of cells or biological molecules studied outside their normal biological context, that is, in a living organism, whereas, ‘in vivo’ terminology includes animal trials and clinical trials in humans. The strength of our product range is that it is supported by a large number of human clinical trials, because humans provide a much better picture of what capabilities can be expected from the probiotics in other humans, compared to animals who often have a very different physiology. In fact, we have recently published a blog that explains how our range of supplements has more finished product clinical (human) trials than any other probiotic brand in the UK: 'Most researched probiotics - Comparing Brands'

    There may, however, be some animal studies carried out on the strains that we use, but we do not advocate this, and we certainly do not conduct these studies ourselves. The fact is that some of the strains in our range are really well known and respected in science, such as L. acidophilus NCFM® and B. lactis BB-12®, so if there is a researcher somewhere in the world who wants to carry out an animal study on probiotics, there’s a high chance they will choose a high quality strain, and this is out of our hands.

    I hope that this answers your question, and thank you for your interest in our products.

    Wishing you the best of health,

  • I am just a little confused. Aren't probiotics a way to heal the stomach and digestion? Than why would people have to be taking it years down the line? Is it a choice or preference? I would think that would be rather burdensome and money spending ongoing seems ridiculous. I would think it would defeat the whole role of what is being illustrated on priobiotics and what they do, what their purpose is, if you seriously had to take them for life. Unless the people taking them, are taking them to be able to eat junk foods and spicy or fatty foods therefore use them, as a means of escape negative affects.

    Please let me know? I am a little off on what direction to go but one thing for sure I don't want something life commitment needed.

  • Hello Jason,

    Thank you for your comments about long-term probiotic usage - I'll try to clarify this a little more for you.

    As this article tries to emphasise, we are all different in our individual needs, not just for probiotics, but for most things: medications, foods, and supplements.

    Whilst probiotics are perfectly safe to take on an ongoing basis long-term, this may not be appropriate or necessary for all users, though it's worth remembering that many aspects of modern life can negatively affect our gut bacteria.

    For example, some people may choose to take a probiotic during and after a course of antibiotic medication, but then find that after a month or two their symptoms have resolved, and a healthy diet and lifestyle helps to keep their flora in good order.

    Others may suffer from chronic health conditions, or be subject to external factors that constantly affect their intestinal flora, and so may decide that taking a probiotic supplement as part of their daily health regime is a helpful ongoing intervention.

    We therefore try to offer as much advice to our customers as possible, so that they decide what may be appropriate for them. If you are still unsure, then we also offer a technical advice service to help you choose the product that best suits your needs, and to decide on the duration and dosage that's right for you.

    Do email us on [email protected] if you'd like to have a chat about your own probiotic needs with us.

    Wishing you the best of health,


  • Wow! Well I'm certainly sold. What a lovely sounding family run company - passionate about what you do! Good for you.

  • Chronic, debilitating rhinitis for at least 20 years. Desperation tried antihistamines and steroid nasal drops both with unpleasant effects. Waiting to see allergy specialist bought Optibac probiotics after reading several articles. After a month with no allergy flareups the allergy specialist admitted I'd found something that had a profound effect for me. It is two years and I am still taking two capsules before breakfast and so far no more rhinitis. Can't believe the change in my life, was so ill as had attack every two weeks. Really feel that many others like me would benefit. Thank you for my life back. Fascinating.

  • Response from OptiBac Probiotics

    Dear Mrs. Pattison,

    Thank you so much for your fabulous feedback.

    With best wishes,


  • So happy with all the products I have purchased, and I do recommend the company to my friends

  • Response from OptiBac Probiotics

    Hello Anne,

    Thank you so much for your lovely feedback - that's fantastic news!
    So pleased that the products are working well for you.

    If you wish to leave feedback about any specific product, then you can do so on each product page.
    See 'How do we collect our product reviews?' https://www.optibacprobiotics.co.uk/faq/how-do-we-collect-our-product-reviews

    Once again, thanks for taking the time to leave your comments.

    Best wishes,

    Nutritional Advisor

Write a comment