For every day - Scientific Research
Clinical research on the strains in OptiBac Probiotics 'For every day''For every day' probiotic strains show potential for Stress - October 2010 - Lactobacillus acidophilus Rosell-52 & Bifidobacterium longum Rosell-175, two of the probiotics in 'For every day' (For daily wellbeing), were demonstrated to be beneficial in an innovative new trial linking gut health and stress levels. Published in the British Journal of Nutrition, this clinical trial found that the two probiotic strains are able to cause beneficial psychological effects in humans. 'These results provide further evidence that gut microflora play a role in stress, anxiety and depression' the French scientist reported. Volunteers were administered with either the two 'For every day' (For daily wellbeing) probiotic strains, or a placebo, every day for 30 days, and then tested for stress and anxiety levels. The probiotic group showed significant improvement in psychological distress, depression, anger-hostility and anxiety.
Source: Mr Messaoudi et al., Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. British Journal of Nutrition, 10.1017/S0007114510004319
Lactobacillus acidophilus Rosell-52 has been shown to have a favourable impact on sleep in the elderly – 2009 - The study included 29 healthy subjects aged 60-81 years old who were given a Lactobacillus helveticus (this is in fact the same, but re-categorised as Lactobacillus acidophilus Rosell-52) fermented milk drink for 3 weeks. The same were then given a ‘wash out period’ and then given a placebo drink. Sleep quality was measured by means of actigraphy and a sleep questionnaire. It was found that the probiotic drink significantly improved the quality of sleep as well as number of waking hours, whereas the placebo didn't.
Yamamura S, Morishima H, Kumano-go T, et al. (2009) The effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly subjects. Eur J Nutr 63, 100–105
Lifelong prebiotic supplementation could extend lifespan by over 30% - April 2008 - An animal study at the Université Henri Poincare Nancy I administered rats with the prebiotics inulin and oligofructose (FOS). Results demonstrated increased survival rates in rats given the prebiotics, and also lower body weight and lower cholesterol when compared to rats in the control group. Within the male rats groups, at 18 months old all animals on prebiotics were still alive, compared to 76% of the rats not on prebiotics.
Source: British Journal of Nutrition Published online ahead of print, 11 Apr 2008, doi: 10.1017/S0007114508975607, "Effects of lifelong intervention with an oligofructose-enriched inulin in rats on general health and lifespan" Authors: P. Rozan, A. Nejdi, S. Hidalgo, J.-F. Bisson, D. Desor, M. Messaoudi
Probiotics ease stress-related gut problems - January 2008 – Leading probiotic firm, Lallemand, led a double-blind study which randomly assigned either probiotics or placebos to 75 volunteers from 18 to 60 years old. Participants who received probiotics Lactobacillus acidophilus Rosell-52 and Bifidobacterium longum Rosell-175 reported considerable reduction in abdominal pain and nausea or vomiting compared to participants in the control group. Authors of the study at the Institut Rosell commented that this probiotic supplement could act on the intestinal microflora, the epithelial barrier, and the immune system in order to improve gastrointestinal problems induced by stress.
Source: Nutrition Research (Elsevier) Volume 28, Issue 1, January 2008, Pages 1-5 "Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: a double-blind, placebo-controlled, randomized trial" Authors: L. Diop, S. Guillou, H. Durand
Clinical Research on probiotics and wellbeing
Synbiotics (both probiotics and prebiotics) reduce risk of colon cancer - February 2007 - A large study sponsored by the EU found that a mix of both probiotics and prebiotics largely modified the composition of the colonic bacterial ecosystem, and could in this way diminish the amount of cancer-promoting bacteria. The number of Clostridium perfringens, a bacterial strain thought to convert dietary substances to carcinogenic compounds, decreased notably in participants given the synbiotic product. Lead author Joseph Rafter stated that use of synbiotics may represent a fine means of “chemoprevention of colon cancer in humans”.
Source: American Journal of Clinical Nutrition Volume 85, Pages 488-496 "Dietary synbiotics reduce cancer risk factors in polypectomised and colon cancer patients"
Probiotics restore bowel flora and improve liver enzymes in alcohol-induced liver injury – December 2008 - A study on 66 Russians with alcoholic psychosis and 24 healthy controls found the alcoholic patients to have significantly less Bifidobacteria and Lactobacilli in their systems than participants without alcoholic psychosis. Giving Bifidobacterium bifidum and Lactobacillus plantarum to the alcoholic patients restored their bowel microbiota, and improved their liver health significantly more than standard therapy on its own.
For an abstract of the study, see http://www.alcoholjournal.org/article/S0741-8329(08)00301-7/abstract
Role of prebiotics in reducing artery hardening & boosting heart health – January 2007 - Researchers at the Human Nutrition Research Centre in Auvergne found that mice given long-chain inulin or an oligofructose-enriched inulin showed significantly reduced levels of triacylglycerol and 30% less atherosclerotic plaque. Atherosclerosis (hardening of the arteries) is a major risk factor in cardiovascular disease, which causes up to 50% of deaths in Europe.
Source: M-H Rault-Nania et al., British Journal of Nutrition, Volume 96, Number 5, Pages 840-844
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Diop, L. et al. (2007) Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: a double-blind, placebo-controlled, randomised trial. Nutrition Research 28.